What is Base Calling in Bioinformatics?

Learn Base Calling definition in bioinformatics with explanation to study “What is Base Calling”. Study base calling explanation with bioinformatics terms to review bioinformatics course for online degree programs.

Base Calling Definition

  • Process in which fluorescent traces of the DNA sequences are read by a computer program that assigns bases for each peak in a chromatogram.

    Essential Bioinformatics by Jin Xiong

Base Calling Explanation

Base calling is the process in which raw data is converted to nucleotide bases and assigned the nucleotide bases to chromatogram peaks. This is performed by base calling software such as Phred which is a highly accurate base calling software program.

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