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What is Synonymous Substitutions in Bioinformatics? PDF Download

Learn Synonymous Substitutions definition in bioinformatics with explanation to study “What is Synonymous Substitutions”. Study synonymous substitutions explanation with bioinformatics terms to review bioinformatics course for online degree programs.

Synonymous Substitutions Definition

  • Nucleotide changes in the coding sequence that do not result in amino acid sequence changes for the encoded protein.

    Essential Bioinformatics by Jin Xiong

Synonymous Substitutions Explanation

A Synonymous substitution is a change in nucleotide base pair in an exon of a gene that translates in to a protein such that the amino acid sequence of the protein remains unchanged. This is due to the degeneracy of genetic code. Such mutations are also known as a silent mutation.

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