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What are Alternate Sigma Factors in Microbiology? PDF | Download eBooks

Learn Alternate Sigma Factors definition in microbiology with explanation to study “What are Alternate Sigma Factors”. Study alternate sigma factors explanation with microbiology terms to review microbiology course for online degree programs.

Alternate Sigma Factors Definition

  • Sigma is the subunit of bacterial RNA polymerase that is required for transcription initiation; alternate sigma factors direct the core RNA polymerase to transcribe distinct sets of inducible genes or operons, and is thereby a mechanism for global regulation.

    Prescott's Microbiology 9th Edition by Joanne Willey, Linda Sherwood, Christopher J. Woolverton

Alternate Sigma Factors Explanation

Alternative sigma factors bind the core catalytic core of the RNA polymerase so that different operons and inducible genes are transcribed and is therefore a means of global regulation. This binding also confers the selection of promoter on holoenzyme. Bacterial RNA polymerase consists of a subunit known as sigma, which is needed for the initiation of transcription.

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