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What is B7 (Cd80) Protein in Microbiology? PDF | Download eBooks

Learn B7 (Cd80) Protein definition in microbiology with explanation to study “What is B7 (Cd80) Protein”. Study b7 (cd80) protein explanation with microbiology terms to review microbiology course for online degree programs.

B7 (Cd80) Protein Definition

  • Single chain glycoprotein expressed on activated T cells, B cells, and macrophages; dendritic cells and peripheral blood monocytes express low levels. B7 binds CD28 on T cells, resulting in second signal activation.

    Prescott's Microbiology 9th Edition by Joanne Willey, Linda Sherwood, Christopher J. Woolverton



B7 (Cd80) Protein Explanation

B7 is a peripheral membrane protein present on APCs or antigen presenting cells which when combined with either a CD152 (CTLA-4) or CD28 surface protein on T-cell produce a co-inhibitory or co-stimulatory signal to decrease or enhance the MHC-TCR signal activity between the T cell and the APC.

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