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A1492 and A1493 Definition and Explanation PDF | Download eBooks

Learn A1492 and A1493 definition in molecular biology with explanation to study “What is A1492 and A1493”. Study a1492 and a1493 explanation with molecular biology terms to review molecular biology course for online degree programs.

A1492 and A1493 Definition:

  • Two universally conserved bases in 16S rRNA that play a critical role in codon-anticodon recognition by inserting into the minor groove between codon and anticodon and stabilizing the interaction..

    Molecular Biology by Robert F. Weaver



A1492 and A1493 Explanation:

A1492 and A1493 are two universally conserved bases in 16S rRNA that are critical for codon - anticodon recognition. These insert into the minor groove, between the codon and anticodon and stabilize the interaction. In the 30S A site of rRNA, A1493C or any substitution of G530 or A1492 leads to the complete loss of translation activity. Whereas, A1493U and A1493G decrease translation activity by >20-fold.

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