What is AAUAAA in Molecular Biology?

Learn AAUAAA definition in molecular biology with explanation to study “What is AAUAAA”. Study aauaaa explanation with molecular biology terms to review molecular biology course for online degree programs.

AAUAAA Definition

  • An important part of the animal polyadenylation signal that dictates cleavage and polyadenylation about 20 nt downstream..

    Molecular Biology by Robert F. Weaver

AAUAAA Explanation

AAUAAA is an important hexamer sequence polyadenylation signal in animals, that causes polyadenylation and cleavage about 20 nt. downstream. Such hexamer sequences are very important, as proven by various in vivo and in vitro experiments. The removal of the AAUAAA sequence or even single nucleotide changes, have proven to impair cleavage efficiency severely.

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