What is Activation Region I (ARI) in Molecular Biology? PDF Book

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Activation Region I (ARI) Definition

  • Region of CAP that is thought to bind to the carboxyl-terminal domain (CTD) of the α-subunit of E. coli RNA polymerase..

    Molecular Biology by Robert F. Weaver



Activation Region I (ARI) Explanation

Activation region I is the region of CAP subunit that binds to the CTD (carboxyl-terminal domain) of the Escherichia Coli RNA polymerase α-subunit. These activating regions, which make contact with the RNA polymerase at promoters, have been located by using genetic methods. In RNA polymerase, the contact site is located in alpha subunit C-terminal domain.

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