As an Amazon Associate I earn from qualifying purchases.

Affinity Labeling Definition and Explanation PDF | Download eBooks

Learn Affinity Labeling definition in molecular biology with explanation to study “What is Affinity Labeling”. Study affinity labeling explanation with molecular biology terms to review molecular biology course for online degree programs.

Affinity Labeling Definition:

  • Labeling one substance by covalently attaching a reactive compound with specific affinity for the first substance (e.g., labeling the active site of an enzyme by linking a labeled substrate analog covalently to the enzyme)..

    Molecular Biology by Robert F. Weaver



Affinity Labeling Explanation:

Affinity labeling is a strategy to chemically modify an amino acid residue, within a ligand-binding site in an enzyme. This can happen either at a regulatory allosteric site or at the active site. The process involves a reagent that structurally resembles the natural ligand of the enzyme, but at the same time features a functional group that is capable of covalently reacting with many different amino acid residues.

Keep Learning Molecular Biology Explanations

What is Anti σ-Factor?

Anti- σ-Factor (anti sigma factor) is an antagonist to the sigma factor that acts by binding to the sigma factor ...

What is Amino Acid?

Amino acids, the building blocks of proteins, are organic compounds, made up of amine and carboxyl functional groups. In addition ...

What is Amber Codon?

Amber codon is a stop codon (a codon responsible for the termination of translation). There are three codon that usually ...

What is Accommodation?

Accommodation is a term that is used to describe the position of aminoacyl-tRNA, which does not bend in the A/T ...

What is Allolactose?

Allolactose consists of monosaccharides D-glucose and D-galactose linked through a β1-6 glycosidic linkage, to form a disaccharide, similar to lactose. ...

What is Alternative Splicing?

Alternative splicing or differential splicing is means splicing of the same pre-RNA in more than one ways, that in turn ...