What is Allele Specific RNAi in Molecular Biology? PDF Book

Learn Allele Specific RNAi definition in molecular biology with explanation to study “What is Allele Specific RNAi”. Study allele specific rnai explanation with molecular biology terms to review molecular biology course for online degree programs.

Allele Specific RNAi Definition

  • Introduction of an altered copy of a gene whose mRNA will not be destroyed by RNAi targeted to the endogenous copy of the gene..

    Molecular Biology by Robert F. Weaver

Allele Specific RNAi Explanation

RNAi (RNA interference) or sequence-specific posttranscriptional gene silencing, is induced by small double stranded RNAs, called small interfering RNA strands (siRNA). These siRNA duplexes have the ability of inhibiting the expression of a specific allele, without interfering with the expression of other alleles. This is called allele-specific silencing or RNAi.

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