What is AP Endonuclease in Molecular Biology? PDF Book

Learn AP Endonuclease definition in molecular biology with explanation to study “What is AP Endonuclease”. Study ap endonuclease explanation with molecular biology terms to review molecular biology course for online degree programs.

AP Endonuclease Definition

  • An enzyme that cuts a strand of DNA on the 5'-side of an AP site..

    Molecular Biology by Robert F. Weaver



AP Endonuclease Explanation

Ap endonuclease stands for Apurinic/apyrimidinic endonuclease, an enzyme that functions in the DNA base revision repair pathway. It cuts a DNA strand on the 5'-side of an AP site. It plays a main role in the repair of mismatched or damaged nucleotides in the DNA, by creating a nick in the phosphodiester backbone of the AP site, when the damaged base is removed by the DNA glycosylase.

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