As an Amazon Associate I earn from qualifying purchases.

APE1 (AP Endonuclease 1) Definition and Explanation PDF | Download eBooks

Learn APE1 (AP Endonuclease 1) definition in molecular biology with explanation to study “What is APE1 (AP Endonuclease 1)”. Study ape1 (ap endonuclease 1) explanation with molecular biology terms to review molecular biology course for online degree programs.

APE1 (AP Endonuclease 1) Definition:

  • A mammalian enzyme that uses its 3'→5' exonuclease activity to edit the errors made by DNA polymerase b during base excision repair..

    Molecular Biology by Robert F. Weaver

APE1 (AP Endonuclease 1) Explanation:

Human apurinic/apyrimidinic endonuclease 1 (APE1) is a mammalian enzyme, that plays a key role in the DNA base excision repair system. It uses its 3'→5'exonuclease activity for the repair of errors made during base excision repair. This enzyme is also recognized as a redox factor.

Keep Learning Molecular Biology Explanations

What is Aconitase?

Aconitase is an enzyme, which, in apoprotein form (iron lacking form) binds to the iron response elements in the messenger ...

What is Architectural Transcription Factor?

Architectural Transcription Factor is a protein that helps the DNA to bend, so that other activators can stimulate transcription. It ...

What is A-DNA?

A-DNA is a form of DNA, a biologically active double helical structure, which is assumed in solution by an RNA-DNA ...

What is Ago3?

Ago3 is an Argonaute protein that is predicted to have mRNA binding activity. Then, in association with piRNAs, it cleaves ...

What is Archaea?

Archaea is the domain of single-celled organisms that are basically prokaryotes, but resemble to the eukaryotes and bacteria in terms ...

What is A Site (RNA Polymerase)?

A' site in the RNA polymerase is an active site of the RNA polymerase, where the phosphodiester-bond is formed during ...