What is APE1 (AP Endonuclease 1) in Molecular Biology? PDF Book

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APE1 (AP Endonuclease 1) Definition

  • A mammalian enzyme that uses its 3'→5' exonuclease activity to edit the errors made by DNA polymerase b during base excision repair..

    Molecular Biology by Robert F. Weaver



APE1 (AP Endonuclease 1) Explanation

Human apurinic/apyrimidinic endonuclease 1 (APE1) is a mammalian enzyme, that plays a key role in the DNA base excision repair system. It uses its 3'→5'exonuclease activity for the repair of errors made during base excision repair. This enzyme is also recognized as a redox factor.

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