What is Apyrimidinic Site (AP Site) in Molecular Biology?

Learn Apyrimidinic Site (AP Site) definition in molecular biology with explanation to study “What is Apyrimidinic Site (AP Site)”. Study apyrimidinic site (ap site) explanation with molecular biology terms to review molecular biology course for online degree programs.

Apyrimidinic Site (AP Site) Definition

  • A deoxyribose in a DNA strand that has lost its pyrimidine base..

    Molecular Biology by Robert F. Weaver



Apyrimidinic Site (AP Site) Explanation

Apyrimidinic Site (AP site) is a site in the DNA molecule which does not have a pyrimidine base. Such situation may occur either due to a DNA damage or spontaneously. It has been estimated that in a cell, under physiological conditions, 500 apyrimidinic sites may be generated daily.

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